产品名称 α-Synuclein Antibody from DENDRITICS SAS
产品货号 DDX0910
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic Specificityα-Synuclein
CloneAS11
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsWB, IF, IHC frozen section
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Descriptiona-synuclein (snca) is a140 aas neuronal protein predominantly present in synaptic junctions, specially studied for its relevance in understanding sporadic and familial forms of Parkinson's disease and related neurodegenerative disorders. In an attempt to break the immunotolerance since the amino-acid sequence is highly conserved between species (95.3% homology between human and mouse), we have immunized C57BL/6 inbred mice presenting a natural deletion for snca with recombinant human a-synuclein and obtained a murine mAb (AS11) recognizing endogenous human a-synuclein. (Kahle et al.,2000, J Neurosci 2000;20:6365-73 ; Specht and Schoepfer, BMC Neurosci 2001;2:11 ; Mougenot AL et al, J Neurosci Methods. 2010 Oct 15;192(2):268-76).
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #DDX0910
Price
Order / More Infoα-Synuclein Antibody from DENDRITICS SAS
Product Specific Referencesn/a
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