| 产品详情 |
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| Product Name | AGTRL1 Activated GPCR Internalization Assay Kit |
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| Description | Activated GPCR Internalization cells are engineered to co-an untagged GPCR, Enzyme Acceptor (EA) tagged β-Arrestin, and a ProLink (PK) tag localized to the endosomes. Activation of the GPCR induces β-Arrestin recruitment, followed by internalization of the Receptor/Arrestin-EA complex in PK-tagged endosomes. This forces complementation of the two β-galactosidase enzyme fragments (EA and PK), forming functional enzyme that hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance. |
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| Size | 100 dp (1 x 96-well)/200 dp (2 x 96-well)/1000 dp (10 x 96-well) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2190 |
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| Order / More Info | AGTRL1 Activated GPCR Internalization Assay Kit from CREATIVE BIOMART |
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| Product Specific References | n/a |
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