| 产品详情 |
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| Antigenic Specificity | DUBA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DUBA Polyclonal Antibody. This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. |
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| Immunogen | n/a |
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| Other Names | DUBA; OTU domain-containing protein 5; deubiquinating enzyme A; deubiquitinating enzyme A |
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| Gene, Accession # | Entrez: 54644, 55593; Uniprot: Q3U2S4, Q96G74 |
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| Catalog # | A302-920A-M |
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| Price | |
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| Order / More Info | DUBA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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