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Antigenic Specificity | Myosin Heavy Chain |
Clone | H11 |
Host Species | Mouse |
Reactive Species | mammalian |
Isotype | IgM |
Format | unconjugated |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Myosin Heavy Chain. Myosin heavy chain is an actin-based motor protein with an approximate molecular weight of 223 kD. Myosin heavy chain can be split into 1 light meromysin and 1 heavy meromysin chain (and further into 2 globular subfragments and 1 rod-shaped subfragment). This protein is highly expressed in muscle. Motor proteins that convert chemical energy derived from ATP hydrolysis into mechanical force that drives motile processes such as cytokinesis, vesicular transport, and cellular locomotion. Myosin heavy chain is modified by acetylation in cysteine residues in the S1 domain for myosin ATPase activity. Muscle myosin is a hexameric protein consisting of 2 heavy chain subunits and 2 alkali light chain subunits and 2 regulatory light chain subunits that forms filaments. |
Immunogen | This antibody was generated against a complex mixture of phosphoproteins extracted from Madin-Darby Canine Kidney Cells. |
Other Names | (Abcam indicates the H11 clone is specific for MYH3) MMS-460R-100 |
Gene, Accession # | n/a |
Catalog # | 922701 |
Price | |
Order / More Info | Myosin Heavy Chain Antibody from BIOLEGEND |
Product Specific References | PubMed: 11815633 |