| 产品详情 |
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| Product Name | LYN-1604 |
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| Description | An activator of ULK1 (EC50 = 18.94 nM); increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 TNBC cells in a concentration-dependent manner, indicating an increase in autophagy; increases the cleavage of the pro-apoptotic protein caspase-3; decreases the viability of MDA-MB-231 cells in vitro (IC50 = 1.66 µM); reduces tumor growth in an MDA-MB-231 mouse xenograft model at 25, 50, and 100 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LYN1604 unc51 ULK-1 LC3II LC-3 p-62 MDAMB231 3MA |
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| Gene, Accession, CAS # | CAS: 2088939-99-3 |
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| Catalog # | 24007-1 |
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| Price | |
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| Order / More Info | LYN-1604 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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