| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | EGLN3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | peptide affinity purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | WB, IHC. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism (By similarity). This EGLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human EGLN3. |
|---|
| Immunogen | Human EGLN3. |
|---|
| Other Names | EGLN3; egl nine homolog 3 (C. elegans); FLJ21620; HIFPH3; MGC125998; MGC125999; PHD3; EGL nine (C.elegans) homolog 3; egl nine homolog 3; egl nine-like protein 3 isoform; HPH-1; Hypoxia-inducible factor prolyl hydroxylase 3; Prolyl hydroxylase domain-containing protein 3; HIF-PH3; HIF-prolyl hydroxylase 3; HPH-3; SM-20; HIFP4H3 |
|---|
| Gene, Accession # | EGLN3, SwissProt: Q9H6Z9 |
|---|
| Catalog # | abx027889 |
|---|
| Price | |
|---|
| Order / More Info | EGLN3 Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|