| 产品详情 |
| Edit |   |
|---|
| Product Name | PF-06409577 |
|---|
| Description | An activator of AMPK heterotrimers (Kd = 9 nM for α1β1γ1); selectively activates β1-containing AMPK isoforms (EC50s = 2.18-7.03 nM) over β2-containing isoforms (EC50s = ≥10 µM); EC50 = 7 nM in an activation/protection TR-FRET assay using α1β1γ1 AMPK; increases phosphorylation of AMPK in rat kidney in vivo at ≥10 mg/kg; decreases urinary albumin levels in a ZSF1 obese rat model of diabetes, metabolic syndrome, and renal disease at 100 mg/kg |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | CAS: 1467057-23-3 |
|---|
| Catalog # | 27366-25 |
|---|
| Price | |
|---|
| Order / More Info | PF-06409577 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|