| 产品详情 |
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| Antigenic Specificity | Caspase 1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:1000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 1 Polyclonal Antibody. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar |
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| Immunogen | n/a |
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| Other Names | ICE, IL1BC, P45, CASP1 nirs variant 1, IL-1 beta-converting enzyme, IL-1BC, IL1B-convertase, caspase-1, interleukin 1-B converting enzyme |
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| Gene, Accession # | Entrez: 834; Uniprot: P29466 |
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| Catalog # | PA5-27387 |
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| Price | |
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| Order / More Info | Caspase 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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