| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase 1 |
|---|
| Clone | 5B10 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1-5 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase 1 Monoclonal Antibody (5B10), eBioscience™. Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts. |
|---|
| Immunogen | n/a |
|---|
| Other Names | ICE, IL1BC, P45 |
|---|
| Gene, Accession # | Entrez: 12362; Uniprot: P29452 |
|---|
| Catalog # | 14-9832-82 |
|---|
| Price | |
|---|
| Order / More Info | Caspase 1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 21862582, 22819539, 23160153, 23986531, 26059659, 26779811, 28701727 |
|---|
| 产品资料 |
|
|