| 产品详情 |
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| Antigenic Specificity | Caspase 1 |
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| Clone | 14F468 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 1 Monoclonal Antibody (14F468). Caspase proteins are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis (1). The precursor form of all caspase proteins is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into tetramer to form the active enzyme. Caspase-1 (ICE, IL-1b converting enzyme) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates multiple proinflammatory cytoki |
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| Immunogen | n/a |
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| Other Names | ICE, IL1BC, P45, CASP1 nirs variant 1, IL-1 beta-converting enzyme, IL1B-convertase, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), caspase-1, interleukin 1, beta, convertase, interleukin 1-B converting enzyme |
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| Gene, Accession # | Entrez: 12362, 25166, 834; Uniprot: P29452, P29466, P43527 |
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| Catalog # | MA5-16215 |
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| Price | |
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| Order / More Info | Caspase 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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