| 产品详情 |
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| Product Name | GDC-0084 |
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| Description | A dual inhibitor of PI3K and mTOR (Kiapps = 2, 46, 3, 10, and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and mTOR, respectively); inhibits the proliferation of PC3 cells in vitro (EC50 = 0.4 µM); reduces phosphorylation of Akt in mouse brain at 25 mg/kg; reduces tumor growth in a U87 MG/M human glioblastoma mouse xenograft model at >2.2 mg/kg and induces tumor regression at 17.9 mg/kg; reduces tumor growth in an A431 cSCC mouse xenograft model at 25 and 50 mg/kg |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1382979-44-3 |
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| Catalog # | 26390-25 |
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| Price | |
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| Order / More Info | GDC-0084 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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