| 产品详情 |
| Edit |   |
|---|
| Product Name | GDC-0084 |
|---|
| Description | A dual inhibitor of PI3K and mTOR (Kiapps = 2, 46, 3, 10, and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and mTOR, respectively); inhibits the proliferation of PC3 cells in vitro (EC50 = 0.4 µM); reduces phosphorylation of Akt in mouse brain at 25 mg/kg; reduces tumor growth in a U87 MG/M human glioblastoma mouse xenograft model at >2.2 mg/kg and induces tumor regression at 17.9 mg/kg; reduces tumor growth in an A431 cSCC mouse xenograft model at 25 and 50 mg/kg |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | CAS: 1382979-44-3 |
|---|
| Catalog # | 26390-1 |
|---|
| Price | |
|---|
| Order / More Info | GDC-0084 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|