| 产品详情 |
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| Product Name | AZD 5438 |
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| Description | A potent inhibitor of Cdk1, Cdk2, and Cdk9 (IC50s = 16, 6, and 20 nM, respectively); inhibits kinase activity of Cdk5/p25 and GSK3β; induces cell cycle arrest by inhibiting phosphorylation of CDK-dependent substrates; has in vivo antiproliferative activity against a range of tumor cell lines (IC50s ranging from 200-1,700 nM); in vivo oral administration inhibits growth of human tumor xenografts and inhibits cell cycle proteins |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AZD5438 Cdk-5 1 2 9 anti-proliferative GSK3b MCF7 ARH77 GSK-3b 3β |
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| Gene, Accession, CAS # | CAS: 602306-29-6 |
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| Catalog # | 21598-50 |
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| Price | |
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| Order / More Info | AZD 5438 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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