| 产品详情 |
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| Product Name | Peficitinib |
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| Description | A JAK inhibitor (IC50s = 3.9, 5, and 0.71 nM for JAK1-3, respectively); 14-fold selective for JAK1 and JAK3 over JAK2 in erythropoietin-induced leukemia cell proliferation assays; inhibits IL-2-induced proliferation of rat splenocytes (IC50 = 10 nM) and phosphorylation of STAT5 in rat and human whole blood (IC50s = 124 and 127 nM, respectively); reduces paw swelling (ED50 = 5.6 mg/kg) and bone destruction in a rat model of adjuvant-induced arthritis at 30 mg/kg |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ASP015K|JNJ-54781532 |
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| Gene, Accession, CAS # | CAS: 944118-01-8 |
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| Catalog # | 22954-10 |
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| Price | |
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| Order / More Info | Peficitinib from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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