| 产品详情 |
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| Antigenic Specificity | CD193 |
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| Clone | J073E5 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-mouse CD193 (CCR3). CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-α receptor like-2, and eotaxin receptor, is a member of the G protein-coupled, seven transmembrane receptor family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CD193 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CD193 is expressed on mouse eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, hematopoietic progenitor cells, and keratinocytes. It is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CD193 also function as a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CD193 has been shown to inhibit HIV infection in some cell types. |
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| Immunogen | Mouse CCR3-transfectants |
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| Other Names | CC CKR3, MIP1-alpha receptor like-2, Eotaxin receptor |
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| Gene, Accession # | Gene ID: 12771 |
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| Catalog # | 144507 |
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| Price | |
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| Order / More Info | CD193 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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