产品详情 |
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Antigenic Specificity | Complement C4b/C4c |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:100, Immunofluorescence: 1:50-1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Complement C4b/C4c Polyclonal Antibody, FITC. This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene clus |
Immunogen | n/a |
Other Names | DAMC-258G8.6, C4, C4A2, C4A3, C4A4, C4A6, C4S, CO4, CPAMD2, MGC164979, RG |
Gene, Accession # | Entrez: 721; Uniprot: P0C0L5 |
Catalog # | PA1-28407 |
Price | |
Order / More Info | Complement C4b/C4c Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25030054 |
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