| 产品详情 |
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| Product Name | Misoprostol (free acid) |
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| Description | Misoprostol is a prostaglandin E1 (Item No. 13010) analog with agonist activity mediated by EP2, EP3, and EP4 receptors.{2313,1754,1752,1611} It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg),{1754} inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM),{1752} and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM){1611} in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; Item No. 10006317) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.{2313} |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PGE1 analogs agonists EP2 EP3 EP4 cytotec cytoprotection SC-29333 SC29333 receptors RU486 RU-486 |
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| Gene, Accession, CAS # | CAS: 112137-89-0 |
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| Catalog # | 13821-5 |
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| Order / More Info | Misoprostol (free acid) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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