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| Antigenic Specificity | Actin Alpha 1, Skeletal Muscle (ACTA1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin. |
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| Immunogen | Human ACTA1/a-actin. |
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| Other Names | ACTA1; Actin, Alpha 1, Skeletal Muscle; Nemaline Myopathy Type 3; ACTA; Actin, Alpha Skeletal Muscle; Alpha-Actin-1; CFTD1; CFTDM; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; Alpha Actin 1; Alpha 1 Actin; Alpha Actin |
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| Gene, Accession # | Accession: NP_001091.1, SwissProt: P68133 |
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| Catalog # | abx028299 |
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| Order / More Info | Actin Alpha 1, Skeletal Muscle (ACTA1) Antibody from ABBEXA |
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| Product Specific References | n/a |
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