| 产品详情 |
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| Antigenic Specificity | ACAP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, equine, human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 0.25-0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ACAP2 Polyclonal Antibody. ACAP2 is a transport carrier belonging to the Centaurin family with three ANK repeats, an Arf-GAP domain, a BAR domain, and a PH domain. ACAP2, a GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) has robust constitutive ARF6 GAP activity, where the GAP activity is stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid but has little activity toward ARF1 and is known to control the return of ARF to the inactive GDB-bound shots. ACAP2, along with ACAP1, is targeted by phosphatidyl inositol (3, 4, 3) triphosphate inhibiting the formation of PDGF-induced dorsal membrane ruffles in NIH3T3 fibroblasts when overexpressed. ACAP2 is phosphorylated upon DNA damage, probably by AT |
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| Immunogen | n/a |
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| Other Names | CENTB2, CNT-B2, Arf GAP with coiled coil, ANK repeat and PH domains 2, arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, centaurin, beta 2, centaurin-beta-2 |
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| Gene, Accession # | Entrez: 100069317, 23527, 488039, 619382, 78618; Uniprot: Q15057, Q5FVC7, Q6ZQK5 |
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| Catalog # | PA5-23302 |
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| Price | |
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| Order / More Info | ACAP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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