| 产品详情 |
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| Product Name | trans-AUCB |
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| Description | Purity >90%. Soluble epoxide hydrolase (sEH) converts epoxides to their corresponding diols. Inhibitors of sEH have anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. trans -AUCB is a very potent inhibitor of sEH (IC50 = 0.5 nM). It displays high oral bioavailability for doses ranging from 0.01 to 1 mg/kg. Dual inhibition of COX-2 and sEH, by celecoxib and trans -AUCB, suppresses tumor angiogenesis, inhibiting tumor growth and metastasis in a Lewis lung carcinoma model in mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[trans -4-[[(tricyclo[3.3.1.13,7 ]dec-1-ylamino)carbonyl]amino]cyclohexyl]oxy]-benzoic acid |
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| Gene, Accession, CAS # | CAS: 885012-33-9 |
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| Catalog # | LS-H10277 |
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| Order / More Info | trans-AUCB from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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