产品名称 Estrogen Receptor 1 (ESR1) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1512877
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityEstrogen Receptor 1 (ESR1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, human
Isotypen/a
Formataffinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionEstrogen receptor alpha (ERalpha), a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ERalpha regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ERalpha activity. ERalpha is phosphorylated on multiple sites. Ser104, 106, 118 and 167 are located in the amino-terminal transcription activation function domain AF-1, and phosphorylation of these serines plays an important role in regulating ERalpha activity. Ser118 may be the substrate of the transcription regulatory kinase CDK7. Ser167 may be phosphorylated by p90RSK and Akt. Phosphorylation of Ser167 may confer tamoxifen resistance in breast cancer patients.Synonyms: ESR1, DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1 , Estrogen Receptor alpha
ImmunogenRecombinant protein of human ESR1
Other NamesACTGP1|ACT1GP1|HY-psi-gamma-AC6|ER[b]2|ER[b]a|zfER[b]2|zfER-beta2|XER|era|esr|esra|nr3a1|ERbeta|xesr-1|ERalpha|xlERalpha1|xlERalpha2|LOC398733|LOC398734|2610524P08Rik|9130407C09Rik|AU019798|Era|M-ERA|MERA-S|MERA-W|ERA|ERAL1A|H-ERA|HERA-A|HERA-B|er|esr1|ER|ESR|ESRA|ESTRR|NR3A1|ER-alpha|Esr|RNESTROR|ERALPHA|ER[a]|eralpha|zfER[a]|ESR1|AA420328|AU041214|ERa|Estr|Estra|Nr3a1
Gene, Accession #Gene ID: 2099,13982,24890
Catalog #ABIN1512877
Price
Order / More InfoEstrogen Receptor 1 (ESR1) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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