产品名称 BACE2C Antibody from BIOVISION, INC.
产品货号 6723-100
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 BIOVISION, INC.
产品概述
产品详情
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Antigenic SpecificityBACE2C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatsaturated ammonium sulfate precipitate
Size100 µl
Concentrationn/a
ApplicationsWestern blot, IHC
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DescriptionPolyclonal Antibody to detect BACE2 in human samples. Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at beta-site and at a different site within Abeta. BACE2 locates on chromosome 21q22.3, the so-called 'Down crit
ImmunogenThis BACE2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-339 amino acids from the C-terminal region of human BACE2C.
Other NamesBACE2; AEPLC; ALP56; ASP21; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Beta-site amyloid precursor protein cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase
Gene, Accession #Gene ID: 25825, Accession: Q9Y5Z0
Catalog #6723-100
Price
Order / More InfoBACE2C Antibody from BIOVISION, INC.
Product Specific Referencesn/a
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