产品详情 |
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Antigenic Specificity | CARMA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CARMA1 Polyclonal Antibody. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced |
Immunogen | n/a |
Other Names | CARD-containing MAGUK protein 1; bcl10-interacting maguk protein 3; card-maguk protein 1; carma 1; caspase recruitment domain-containing protein 11 |
Gene, Accession # | Entrez: 84433; Uniprot: Q9BXL7 |
Catalog # | A302-541A-T |
Price | |
Order / More Info | CARMA1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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