| 产品详情 |
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| Product Name | Glyburide (potassium salt) |
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| Description | A sulfonylurea; an inhibitor of SUR1 linked to Kir6.2 (IC50 = 4.3 nM); binds to RINm5F microsomes (Kd = 0.3 nM); inhibits 86Rb+ efflux from intact RINm5 cells (K0.5 = 0.06 nM); reduces blood glucose levels and increases the activity of hepatic GST and G6PDH in an STZ-induced rat model of diabetes at 5 mg/kg; inhibits ATP-induced increases in caspase-1 activation and IL-1β and IL-18 secretion in a concentration-dependent manner in LPS-primed BMDMs; reduces lesion growth in mice infected with L. mexicana at 80 mg/ml |
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| Size | 10 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Glibenclamide |
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| Gene, Accession, CAS # | CAS: 52169-36-5 |
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| Catalog # | 15009-10 |
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| Order / More Info | Glyburide (potassium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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