产品名称 ATXN3 Antibody from SICGEN ANTIBODIES
产品货号 AB0089-500
产品价格 现货询价,电话:010-67529703
产品规格 1.5 mg
产品品牌 SICGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityATXN3
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotypen/a
Formatimmunoaffinity purified
Size1.5 mg
Concentration3 mg/ml
ApplicationsWB
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DescriptionGoat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder. Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot.
ImmunogenPurified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Other NamesAT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein
Gene, Accession #ATXN3, Gene ID: 4287
Catalog #AB0089-500
Price
Order / More InfoATXN3 Antibody from SICGEN ANTIBODIES
Product Specific Referencesn/a
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