| 产品详情 |
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| Antigenic Specificity | DOK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. DOK2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. This DOK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human DOK1. |
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| Immunogen | Human DOK1. |
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| Other Names | docking protein 1; 62kDa (downstream of tyrosine kinase 1); DOK1; MGC117395; MGC138860; P62DOK; Downstream of tyrosine kinase 1; p62(dok); pp62; p62 (dok) |
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| Gene, Accession # | SwissProt: Q99704 |
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| Catalog # | abx033622 |
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| Price | |
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| Order / More Info | DOK1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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