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| Product Name | TCN 238 |
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| Description | An orally bioavailable positive allosteric modulator of mGluR4 (EC50 = 1 µM); has a greater than 30-fold selectivity for mGluR4 over mGluR5 in vitro; has no activity at concentrations up to 10 µM at A2A, 5-HT1A, or α2A-adrenergic receptors; reduces catalepsy in a haloperidol-induced catalepsy rat model of Parkinson's disease (ED50 = ~1 mg/kg); leads to downregulation of GRM4 and GABRA1 in rat brain without affecting hippocampal-dependent memory |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TCN238 human rat motor dysfunction |
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| Gene, Accession, CAS # | CAS: 125404-04-8 |
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| Catalog # | 11994-25 |
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| Price | |
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| Order / More Info | TCN 238 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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