产品详情 |
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Antigenic Specificity | QPCT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, ovine, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | QPCT Polyclonal Antibody. QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% |
Immunogen | n/a |
Other Names | Glutaminyl-peptide cyclotransferase, GCT, QC, sQC |
Gene, Accession # | Entrez: 100070174, 100338215, 100718225, 25797, 281437, 313837, 403861, 443019, 70536; Uniprot: Q16769, Q28120, Q9CYK2 |
Catalog # | PA5-43215 |
Price | |
Order / More Info | QPCT Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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