| 产品详情 |
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| Antigenic Specificity | MAP2K3 (pS189) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAP2K3 (pS189) Antibody is a Rabbit Polyclonal antibody against MAP2K3 (pS189). MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase. MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines. Activation of MKK3 and MKK6 occurs through phosphorylation of Ser189 and Thr193 on MKK3 and Ser207 and Thr211 on MKK6. |
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| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S189 of human MAP2K3. |
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| Other Names | dual specificity mitogen-activated protein kinase kinase 3; kinase MKK3; MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MEK3; MP2K3; PRKMK3; MAPKK3; MEK 3; mitogen-activated protein kinase kinase 3; MKK3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2; SKK2; MAP2K3 protein; Mapk/Erk Kinase 3 Map2K3 Mek3 |
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| Gene, Accession # | MAP2K3, MAP2K6, Gene ID: 5606, SwissProt: P46734 |
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| Catalog # | abx000143 |
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| Price | |
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| Order / More Info | MAP2K3 (pS189) Antibody from ABBEXA |
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| Product Specific References | n/a |
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