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| Product Name | K 252a |
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| Description | Non-selective protein kinase inhibitor; analog of staurosporine (Cat.No. 1285). Inhibits PKC (IC50 = 32.9 nM), Ca2+/calmodulin-stimulated phosphodiesterases (IC50 = 1.3 - 2.9 μM), MLCK (Ki = 20 nM) and receptor tyrosine kinases. Inhibits the oncogenic properties of MET; prevents autophosphorylation and activation of downstream effectors (MAPK, Akt). Purity 98%. MW (observed): 467.48 |
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| Size | 200 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester. SF 2370 |
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| Gene, Accession, CAS # | CAS: 99533-80-9 |
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| Catalog # | 1683/200U |
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| Price | |
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| Order / More Info | K 252a from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21143600, 23389690, 24611998, 25052836, 25341622, 25710032 |
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