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Product Name | U 73122 |
Description | Phospholipase C inhibitor. Inhibits agonist-induced platelet aggregation with IC50 values of 1-5 μM. Potently inhibits human polymorphonuclear neutrophil adhesion on biological surfaces (IC50 < 50 nM) and exhibits antinociceptive activity in vivo. Also activates TRPM4 and inhibits TRPM3 channels. Negative Control also available.. Purity 98%. MW (observed): 464.65 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione |
Gene, Accession, CAS # | CAS: 112648-68-7 |
Catalog # | 1268/50 |
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Order / More Info | U 73122 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 12538871, 15257286, 15302681, 15306230, 15901799, 17408433, 17494631, 17675102, 18171995, 18253052, 18305089, 19066214, 19186170, 19570026, 19666830, 19725970, 20435001, 20519319, 20685973, 20717650, 21068362, 21179559, 21441943, 21559478, 22291020, 22292038, 22524543, 22542181, 22700794, 23066089, 23097044, 23143333, 23185493, 23235155, 23349021, 23407955, 23749147, 23873842, 24121509, 24258815, 24266887, 24335212, 24463606, 24518663, 24572089, 24762669, 24908484, 25052836, 25112874, 25181481, 25481381, 25633224, 25672589, 25710879, 25751534, 25790461, 25873305, 25938462, 26020477, 26133167, 26269634, 26290782, 26489864, 26617529, 26640326, 26725955, 26909238, 27482714, 27876620, 28800762, 28963439, 29038531 |
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