产品详情 |
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Product Name | STF 083010 |
Description | Inhibitor of IRE1α endonuclease activity; blocks endogenous XBP1 mRNA splicing. Displays cytostatic and cytotoxic effects in CD138+ multiple myeloma (MM) cells in vitro; inhibits bortezomib-induced XBP1 activity in myeloma xenografts in vivo. Does not alter IRE1α kinase activity. Purity 98%. MW (observed): 317.38 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide |
Gene, Accession, CAS # | CAS: 307543-71-1 |
Catalog # | 4509/10 |
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Order / More Info | STF 083010 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25821218 |
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