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Product Name | Stattic |
Description | Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Purity 99%. MW (observed): 211.19 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-Nitrobenzo[b]thiophene 1,1-dioxide |
Gene, Accession, CAS # | CAS: 19983-44-9 |
Catalog # | 2798/50 |
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Order / More Info | Stattic from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19153190, 22689141, 22976953, 23693126, 23729642, 23942241, 24098399, 24945434, 25105067, 25339752, 25582338, 26996579, 27491076, 27978828, 29312598 |
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