| 产品详情 |
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| Product Name | GSK 583 |
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| Description | Potent RIP2 kinase inhibitor (IC50 values are 2 and 5 nM at rat and human kinases, respectively). Displays selectivity for RIP2K over p38α, VEGFR2 and a panel of 300 kinases. Exhibits some inhibition at BRK and Aurora A. Also displays similar binding affinity, but no detectable functional activity at RIP3. Active in vivo. Moderately orally bioavailable and cell permeable. Purity 98%. MW (observed): 398.45 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
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| Gene, Accession, CAS # | CAS: 1346547-00-9 |
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| Catalog # | 6480/25 |
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| Price | |
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| Order / More Info | GSK 583 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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