产品详情 |
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Product Name | GSK 429286 |
Description | Selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin-induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose-dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Purity 97%. MW (observed): 432.37 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-(Trifluoromethyl)phenyl]-N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide. GSK429286A |
Gene, Accession, CAS # | CAS: 864082-47-3 |
Catalog # | 3726/50 |
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Order / More Info | GSK 429286 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 28486133 |
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