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| Product Name | GSK 429286 |
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| Description | Selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin-induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose-dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Purity 97%. MW (observed): 432.37 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[4-(Trifluoromethyl)phenyl]-N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide. GSK429286A |
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| Gene, Accession, CAS # | CAS: 864082-47-3 |
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| Catalog # | 3726/10 |
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| Order / More Info | GSK 429286 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28486133 |
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