| 产品详情 |
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| Product Name | GSK 2193874 |
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| Description | Potent and selective TRPV4 antagonist (IC50 values are 2 and 40 nM for rat and human receptors, respectively); inhibits Ca2+ influx through TRPV4 channels. Prevents and reverses pulmonary edema after myocardial infarction in vivo models. Selective over a panel of ~200 human receptors, channels and enzymes. Orally active. Purity 98%. MW (observed): 691.62 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide |
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| Gene, Accession, CAS # | CAS: 1336960-13-4 |
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| Catalog # | 5106/5 |
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| Price | |
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| Order / More Info | GSK 2193874 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26961876, 27191895 |
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| 产品资料 |
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