| 产品详情 |
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| Product Name | GSK 1363089 |
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| Description | Potent inhibitor of MET, VEGFR2, Ron and AXL (IC50 values are 0.4, 0.9, 3 and 11 nM, respectively). Also potently inhibits Tie-2, Flt-1, Flt-3, Flt-4, KIT, PDGFRα and PDGFRβ. Inhibits migration and invasion of B16F10 melanoma cells in vitro. Suppresses B16F10 tumor growth and metastasis in mice. Orally available. Purity 98%. MW (observed): 632.65 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide. XL 880, EXEL 2880, Foretinib |
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| Gene, Accession, CAS # | CAS: 849217-64-7 |
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| Catalog # | 6056/10 |
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| Price | |
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| Order / More Info | GSK 1363089 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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