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| Product Name | JLK 6 |
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| Description | Inhibitor of γ-secretase that selectively inhibits βAPP cleavage without affecting other γ-secretase-mediated pathways. Prevents recovery of Aβ40 and Aβ42 from HEK293 cell overexpressing wild-type or Swedish-mutated βAPP (IC50 ~ 30 μM) but displays no effect on Notch cleavage and Notch-mediated intracellular signaling. Displays no activity on BACE1, BACE2, α-secretase, the proteosome or GSK3β. Purity 99%. MW (observed): 225.63 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Amino-4-chloro-3-methoxy-1H-2-benzopyran |
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| Gene, Accession, CAS # | CAS: 62252-26-0 |
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| Catalog # | 2677/10 |
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| Price | |
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| Order / More Info | JLK 6 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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