产品详情 |
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Product Name | SIS3 |
Description | Selective Smad3 inhibitor; attenuates TGF-β1-dependent Smad3 phosphorylation and DNA binding. Has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. Inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Also inhibits TGF-β2-induced endothelial cell differentiation in iPSCs. Purity 98%. MW (observed): 489.99 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride |
Gene, Accession, CAS # | CAS: 521984-48-5 |
Catalog # | 5291/50 |
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Order / More Info | SIS3 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 23635013, 27320041 |
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