| 产品详情 |
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| Product Name | Adaptaquin |
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| Description | An inhibitor of PHD2 (IC50 = 2 µM in a reporter assay using SH-SY5Y-ODD-Luc cells); stabilizes HIF-1α protein and induces expression of EPO and VEGF in SH-SY5Y human neuroblastoma cells; protects against glutathione depletion-induced cell death in rat primary cortical neurons (IC50 = 0.25 µM); reduces glutamate-induced cell death in HT-22 cells; increases pellet retrieval in the single-pellet reaching task in a a rat autologous striatal blood infusion model of intracerebral hemmorhage and normalizes preference for ipsilateral turns in a mouse model of striatal hemorrhage at 30 mg/kg |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | adaptoquin hydroxyquinoline PHD ATF4 PHD-2 HIF1α HT22 SHSY5Y |
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| Gene, Accession, CAS # | CAS: 385786-48-1 |
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| Catalog # | 19720-50 |
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| Price | |
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| Order / More Info | Adaptaquin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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