产品详情 |
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Product Name | SEN 12333 |
Description | α7 nicotinic acetylcholine receptor (nAChR) agonist (EC50 = 1.6 μM, Ki = 260 nM at rat α7 nAChRs). Also displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. Brain penetrant and orally bioavailable. Purity 99%. MW (observed): 339.43 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide. WAY 317538 |
Gene, Accession, CAS # | CAS: 874450-44-9 |
Catalog # | 4441/10 |
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Order / More Info | SEN 12333 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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