产品详情 |
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Product Name | KML 29 |
Description | Highly selective and potent monoacylglycerol lipase (MAGL) inhibitor. Exhibits potent inhibition of human, mouse and rat MAGL (IC50 values are 5.9, 15 and 43 nM, respectively). Exhibits no detectable inhibition of FAAH (IC50 > 50000 nM). Potently and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50 = 2.5 nM and >50 μM for 2-AG and AEA respectively). Purity 98%. MW (observed): 549.42 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester |
Gene, Accession, CAS # | CAS: 1380424-42-9 |
Catalog # | 4872/50 |
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Order / More Info | KML 29 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 27553121 |
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