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| Product Name | Cucurbitacin I |
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| Description | Selective inhibitor of STAT3/JAK2 signaling. Inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Suppresses phosphotyrosine levels of STAT3, inhibits STAT3 DNA binding and STAT3-mediated gene expression. Induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3. Purity 95%. MW (observed): 514.65 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (9β,10α,16α,23E)-2,16,20,25-Tetrahydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione. Elatericin B, JSI 124 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 1571/1 |
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| Price | |
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| Order / More Info | Cucurbitacin I from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19421183, 21198545, 21994466, 23262510, 25263555, 26619345, 27109105 |
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| 产品资料 |
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