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| Product Name | CY 09 |
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| Description | NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM). Purity 98%. MW (observed): 423.43 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid |
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| Gene, Accession, CAS # | CAS: 1073612-91-5 |
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| Catalog # | 6436/50 |
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| Price | |
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| Order / More Info | CY 09 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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