产品详情 |
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Product Name | Leptomycin B |
Description | Antifungal antibiotic that is an inhibitor of the nuclear export of proteins; acts by binding directly to and inhibiting CRM1/exportin-1. Inhibits the nuclear export of the HIV regulatory protein Rev and stabilizes p53. Antitumor in vitro and in vivo. MW (observed): 540.74. |
Size | 5 ug |
Concentration | n/a |
Applications | n/a |
Other Names | (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid. CI 940, LMB |
Gene, Accession, CAS # | CAS: 87081-35-4 |
Catalog # | 1987/5U |
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Order / More Info | Leptomycin B from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22345442, 23345332, 24741102 |
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