产品详情 |
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Product Name | Leflunomide |
Description | Inhibitor of dihydroorotate dehydrogenase (IC50 = 2.5 μM). Inhibits de novo pyrimidine synthesis in human T cells in vitro; also inhibits lymphocyte proliferation. Exhibits efficacy in several animal models of autoimmune disease, arthritis and graft rejection. Active metabolite, teriflunomide (A77 1726, Cat. No. 5069), also available. Purity 99%. MW (observed): 270.21 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide. HWA 486, RS-34821 |
Gene, Accession, CAS # | CAS: 75706-12-6 |
Catalog # | 2228/50 |
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Order / More Info | Leflunomide from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21460123 |
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