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Product Name | LE 135 |
Description | Retinoic acid antagonist; displays moderate selectivity for RARβ over RARα (Ki values are 0.22 and 1.4 μM respectively). Highly selective over RARγ and RXRα. Inhibits human HL-60 leukemia cell differentiation induced by Am80 (IC50 = 150 nM). Purity 97%. MW (observed): 438.56 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid |
Gene, Accession, CAS # | CAS: 155877-83-1 |
Catalog # | 2021/50 |
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Order / More Info | LE 135 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 17620362, 19538480, 20944006, 21307853, 21685476, 23345238, 23437413, 23527272, 24384390, 24790153, 26173116, 26587591, 26967733, 27611191, 28087637 |
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