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Antigenic Specificity | ASXL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ASXL1 Polyclonal Antibody. Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A mon |
Immunogen | n/a |
Other Names | Putative Polycomb group protein ASXL1; Additional sex combs-like protein 1; ASXL1; KIAA0978 |
Gene, Accession # | Entrez: 228790; Uniprot: P59598 |
Catalog # | PA5-71475 |
Price | |
Order / More Info | ASXL1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |