| 产品详情 |
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| Antigenic Specificity | ASXL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ASXL1 Polyclonal Antibody. Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A mon |
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| Immunogen | n/a |
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| Other Names | Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978 |
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| Gene, Accession # | Entrez: 171023, 228790, 311553; Uniprot: P59598, Q8IXJ9 |
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| Catalog # | PA5-78828 |
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| Price | |
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| Order / More Info | ASXL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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